Hippocampal subfield volumes in major depressive disorder and bipolar disorder
نویسندگان
چکیده
منابع مشابه
Subcortical volumes differentiate Major Depressive Disorder, Bipolar Disorder, and remitted Major Depressive Disorder.
Subcortical gray matter regions have been implicated in mood disorders, including Major Depressive Disorder (MDD) and Bipolar Disorder (BD). It is unclear, however, whether or how these regions differ among mood disorders and whether such abnormalities are state- or trait-like. In this study, we examined differences in subcortical gray matter volumes among euthymic BD, MDD, remitted MDD (RMD), ...
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BACKGROUND Although genetic epidemiological studies have confirmed increased rates of major depressive disorder among the relatives of people with bipolar affective disorder, no report has compared the clinical characteristics of depression between these two groups. AIMS To compare clinical features of depressive episodes across participants with major depressive disorder and bipolar disorder...
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Relative to healthy controls, lithium free bipolar patients exhibit significant gray matter abnormalities. Lithium, the long-time reference standard medication treatment for bipolar disorder, has been proposed to be neuro-protective against these abnormalities. However, its effects on cortical thickness and hippocampal subfield (HSF) volumes remain unstudied and unclear, respectively, in bipola...
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BACKGROUND Mitochondria provide most of the energy for brain cells by the process of oxidative phosphorylation. Mitochondrial abnormalities and deficiencies in oxidative phosphorylation have been reported in individuals with schizophrenia (SZ), bipolar disorder (BD), and major depressive disorder (MDD) in transcriptomic, proteomic, and metabolomic studies. Several mutations in mitochondrial DNA...
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The lifetime prevalence rates of unipolar depression (UPD) in males and females of first-world countries are approximately 15 and 25 percent, respectively. The figures appear to be equally disheartening in developing countries: The 12-month prevalence of major depressive disorder in South Africa is roughly 5 percent. It is therefore not surprising that 25 percent of all visits to health care pr...
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ژورنال
عنوان ژورنال: European Psychiatry
سال: 2019
ISSN: 0924-9338,1778-3585
DOI: 10.1016/j.eurpsy.2019.01.016